Iowa State vs. Lipscomb Prediction, Odds, Picks - NCAA Tournament First Round (2025)

Updated Mar. 21, 2025 10:27 a.m. ET

Data Skrive

A first-round NCAA Tournament matchup will see the No. 3-seed Iowa State Cyclones (24-9) hit the court against the No. 14 seed Lipscomb Bisons (25-9) on Friday at Fiserv Forum. The contest tips off at 1:30 p.m. ET, on TNT.

The Cyclones are a double-digit favorite against the Bisons when the Cyclones and the Bisons square off. The Cyclones are favored by 14.5 points. The matchup's over/under is set at 143.5.

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Keep reading to get all the information before betting on the Iowa State-Lipscomb matchup.

Iowa State vs. Lipscomb Game Information & Odds

  • When: Friday, March 21, 2025 at 1:30 p.m. ET
  • Where: Fiserv Forum in Milwaukee, Wisconsin
  • How to watch on TV: TNT
  • Live boxscore on FOX Sports
Cyclones vs Bisons Betting Information
Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
Cyclones -14.5 -105 -115 143.5 -110 -120 -1351 +800

Iowa State vs. Lipscomb Prediction

  • Pick ATS: Lipscomb (+14.5)
  • Pick OU: Over (143.5)
  • Prediction: Iowa State 80, Lipscomb 67

Learn more about the Iowa State Cyclones vs. the Lipscomb Bisons game on FOX Sports!

Iowa State vs. Lipscomb Betting Insights

Betting Line Implied Predictions

  • Per the spread and over/under, the implied score for the matchup is Cyclones 79, Bisons 64.
  • The Cyclones have a 93.1% chance to win this contest per the moneyline's implied probability.
  • The Bisons hold an 11.1% implied probability to win.

Key Spread Facts

  • Iowa State has compiled a 19-14-0 ATS record so far this year.
  • Lipscomb has put together a 17-13-1 record against the spread this season.
  • Iowa State has an ATS record of 5-6 when playing as at least 14.5-point favorites this season.
  • Lipscomb has not covered the spread when an underdog by 14.5 points or more this season (in two opportunities).

Key Total Facts

  • Cyclones games have finished with more than 143.5 points 16 times so far this year.
  • So far this season, 15 Bisons games have featured over 143.5 points scored.
  • The Cyclones and Bisons average 159.7 points per game combined, which is 16.2 more than the over/under for this matchup.

Key Moneyline Facts

  • Iowa State has been favored on the moneyline 24 times this season. They've gone 19-5 in those games.
  • Lipscomb has been underdogs in seven games this season and won two (28.6%) of those contests.
  • Iowa State has gone 6-1 when playing as a moneyline favorite with odds of -1351 or shorter (winning 85.7%).
  • Lipscomb has played as an underdog of +800 or more once this season and lost that game.
FINAL LIP 55 · ISU 82 NCAA BK SPREADTO WINTOTAL14 Lipscomb Bisons LIP 3 Iowa State Cyclones ISU

Iowa State vs. Lipscomb: 2024-25 Stats Comparison

Iowa State Lipscomb
Points Scored Per Game (Rank) 80.4 (34) 79.3 (51)
Points Allowed (Rank) 68.1 (63) 67.3 (49)
Rebounds (Rank) 8.8 (181) 7 (324)
3pt Made (Rank) 7.7 (173) 9.9 (27)
Assists (Rank) 15 (79) 15.1 (76)
Turnovers (Rank) 11.5 (219) 9.1 (12)

Iowa State 2024-25 Key Players

Cyclones Leaders
Name GP PTS REB ASST STL BLK 3PM
Curtis Jones 32 17.1 4.3 2.3 1.2 0.2 2.6
Keshon Gilbert 29 13.4 3.5 4.1 1.7 0.1 0.9
Joshua Jefferson 33 13 7.4 3 2.1 0.7 0.5
Milan Momcilovic 26 11.4 3.2 0.9 0.4 0.3 2.2
Tamin Lipsey 32 10.8 2.6 3.2 2.1 0.2 1.2

Lipscomb 2024-25 Key Players

Bisons Leaders
Name GP PTS REB ASST STL BLK 3PM
Jacob Ognacevic 34 20.1 8.1 1.4 0.3 0.4 1.4
Will Pruitt 34 13.2 5.9 2.6 0.9 0.3 1.4
Joe Anderson 34 12.4 3.6 3.9 2.3 0.2 2.2
Gyasi Powell 34 11.7 3.6 1.4 1 0.1 2.2
Dylan Faulkner 15 10.5 5.3 2 0.5 1.6 0

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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